How are Pharmacogenetic Tests Incorporated into Care at Wholeview?

Wholeview medical providers may use pharmacogenetic testing to assist in personalizing medication plans for our patients with mental health conditions. These tests analyze our patient’s genetic profile to predict how they may metabolize or respond to specific medications.

Here’s some information about the test we use and how we think it is helpful to some of our patients.

 How Pharmacogenetic Testing Works

1. Sample Collection: A DNA sample is collected via a cheek swab at home using a collection kit.
2. Genetic Analysis: The sample is analyzed in a lab to identify genetic variations that affect pharmacokinetics (how the body processes medications) and pharmacodynamics (how medications affect the body).
3. Report Generation: The test generates a report categorizing medications into three groups:

• Medications likely to work well.
• Medications requiring caution or dose adjustments.
• Medications likely to be less effective or cause side effects.

 How Does Pharmacogenetic Testing Enhance Addiction Treatment at Wholeview?

• Faster Medication Matching

  : Genetic testing can reduce the trial-and-error process of finding effective psychiatric medications, which is particularly valuable for patients with co-occurring substance use and mental health disorders. This can lead to quicker stabilization of mental health symptoms, potentially reducing reliance on substances as coping mechanisms.

• Dual Diagnosis Support

  : Many patients with substance use disorders also struggle with mental health disorders like depression or anxiety. By identifying effective medications, the test can support comprehensive dual-diagnosis treatment.

• Improved Adherence

  : Patients are more likely to adhere to treatment when they experience fewer side effects or find their medications effective sooner.

 What are the Limitations of Pharmacogenetic Testing?

• Supplementary Tool: Genetic testing is not a standalone solution. We use it alongside a thorough clinical evaluation, including medical history, family history, and other relevant factors.
• Cost and Accessibility: Routine genetic testing for all patients is not cost-effective. Some insurance plans require prior medication failures before covering the test.
• Efficacy Variability: While studies show improved response and remission rates at early stages of treatment, long-term outcomes may not differ significantly from standard care without pharmacogenomic testing.

 How Does Wholeview Incorporate These Tests into Care at Wholeview? 

• Genetic testing is discussed as an option with patients who have struggled with medication side effects or inefficacy.
• Our integrated approach to care uses genetic tests in combination with therapy, behavioral interventions, and other medical treatments.
• We educate our patients about the test’s role in optimizing their care plan while sharing realistic information about its benefits. This helps patients decide if they are interested in testing.

 In Summary

Overall, we believe that incorporating genetic testing into care can be a valuable tool in personalizing psychiatric care for our patients, which helps to address co-occurring mental health issues more efficiently and effectively. These tests are especially important when used carefully in a targeted fashion and integrated into our broader treatment strategies.